Skip to main content

Mannose Receptor

Function

Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

Tissue specificity

Detected in macrophages.

Cellular localization

  • Endosome membrane
  • Single-pass type I membrane protein
  • Cell membrane
  • Single-pass type I membrane protein

Alternative names

CD206, Macrophage mannose receptor 1, MMR, Mrc1

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

164981Da