MRM1
Function
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
Sequence Similarities
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Cellular localization
- Mitochondrion matrix
Alternative names
16S rRNA (guanosine(1145)-2'-O)-methyltransferase, 16S rRNA [Gm1145] 2'-O-methyltransferase, MRM1