MRPS27
Function
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis (PubMed:22841715). Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain (PubMed:22841715). Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu) (PubMed:22841715). Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:28714366).
Sequence Similarities
Belongs to the mitochondrion-specific ribosomal protein mS27 family.
Tissue Specificity
Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level) (PubMed:28714366). Ubiquitous (PubMed:22841715).
Cellular localization
- Cytoplasm
- Mitochondrion
Alternative names
KIAA0264, MRPS27, Small ribosomal subunit protein mS27, Mitochondrial ribosomal protein S27, MRP-S27, S27mt