B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Phosphorylated. Might be functionally regulated by protein kinase(s) (By similarity).
Belongs to the MS4A family.
Expressed in PBMCs and lymph node from healthy dogs, in B-cells of canine lymphoma, but not in T-cell lymphoma cells and non-T and non-B-cell lymphoma cells.
CD20, MS4A1, B-lymphocyte antigen CD20, Membrane-spanning 4-domains subfamily A member 1
Proteins
Immunology & Infectious Disease
33056Da
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