Msr1

Function

Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL).

Cellular localization

• Membrane
• Single-pass type II membrane protein

Alternative names

CD204, Scvr, Msr1, Macrophage scavenger receptor types I and II, Macrophage acetylated LDL receptor I and II, Scavenger receptor type A, SR-A

Database links

swissprot:P30204 entrezGene:20288

Other research areas

• Immuno-oncology