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MSR1
Function
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL).
Cellular localization
- Membrane
- Single-pass type II membrane protein
Alternative names
- Macrophage scavenger receptor types I and II
- Macrophage acetylated LDL receptor I and II
- Scavenger receptor type A
- SR-A
- Scvr
- Msr1
Database links
Target type
Proteins
Primary research area
Immunology & Infectious Disease
Other research areas
- Immuno-oncology
Molecular weight
50170Da