Mst1
Developmental stage
Is expressed at low levels during gestation. Just before birth the level increases dramatically and remains stable afterwards.
Post-translational modifications
Cleaved after Arg-488, probably by HPN/Hepsin, to yield the active form consisting of two disulfide-linked chains.
Sequence Similarities
Belongs to the peptidase S1 family. Plasminogen subfamily.
Tissue Specificity
Liver. Lower levels in lung, placenta and adrenal.
Cellular localization
- Secreted
Alternative names
Hgfl, Mst1, Hepatocyte growth factor-like protein, Macrophage stimulatory protein, MSP