High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Belongs to the G-protein coupled receptor 1 family.
Expressed in retina and less in brain and hippocampus.
Melatonin receptor type 1B, Mel-1B-R, Mel1b receptor, MTNR1B
Proteins
Metabolism
40188Da
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