MTPN
Function
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy.
Sequence Similarities
Belongs to the myotrophin family.
Tissue Specificity
Ubiquitous.
Cellular localization
- Cytoplasm
- Nucleus
- Cytoplasm
- Perinuclear region
Alternative names
Myotrophin, Protein V-1, MTPN