MTUS2
Function
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
Sequence Similarities
In the C-terminal section; belongs to the MTUS1 family.
Tissue Specificity
Detected in embryonic stem cells differentiating to cardiomyocytes.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules.
Alternative names
CAZIP, KIAA0774, TIP150, MTUS2, Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Microtubule plus-end tracking protein TIP150, Tracking protein of 150 kDa