MYBL2 phospho S577 + S581
Function
Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
Post-translational modifications
Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.
Cellular localization
- Nucleus
Alternative names
BMYB, MYBL2, Myb-related protein B, B-Myb, Myb-like protein 2