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MYBL2 phospho T487

Function

Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.

Post-translational modifications

Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.

Cellular localization

  • Nucleus

Alternative names

  • Myb-related protein B
  • B-Myb
  • Myb-like protein 2
  • MYBL2
  • BMYB

Target type

Proteins

Primary research area

Epigenetics

Molecular weight

78764Da