Fast Myosin Skeletal Heavy chain

The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.

Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).

Muscle contraction.

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

• Cytoplasm
• Myofibril
• Thick filaments of the myofibrils.

Myosin-1, Myosin heavy chain 1, Myosin heavy chain 2x, Myosin heavy chain IIx/d, MyHC-2x, MyHC-IIx/d, MYH1

• entrezGene:4620
• entrezGene:4619
• entrezGene:4621
• entrezGene:4632
• entrezGene:4633
• entrezGene:4634
• entrezGene:4635
• entrezGene:4636
• entrezGene:4637
• entrezGene:4624
• entrezGene:4622
• omim:160780
• omim:160740
• omim:160730
• swissprot:P12882
• swissprot:Q9UKX2
• swissprot:Q02045
• swissprot:P60660
• swissprot:P11055
• swissprot:P13533
• swissprot:P10916
• swissprot:Q9Y623
• swissprot:P12829
• swissprot:P05976
• swissprot:P08590

Proteins

Cardiovascular

223145Da