MYL12A
Function
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).
Post-translational modifications
Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge (By similarity).
Alternative names
MLCB, MRLC3, RLC, MYL12A, Myosin regulatory light chain 12A, Epididymis secretory protein Li 24, MLC-2B, Myosin RLC, Myosin regulatory light chain MRLC3, HEL-S-24