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MYL4

Function

Regulatory light chain of myosin. Does not bind calcium.

Involvement in disease

Atrial fibrillation, familial, 18

ATFB18

A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure.

None

The disease is caused by variants affecting the gene represented in this entry.

Alternative names

MLC1, PRO1957, MYL4, Myosin light chain 4, Myosin light chain alkali GT-1 isoform

swissprot:P12829 omim:160770 entrezGene:4635