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MYO19

Domain

The MyMOMA (MYO19-specific mitochondrial outer membrane-association) region mediates association with the mitochondrion outer membrane via electrostatic interaction.

Function

Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed:19932026, PubMed:23568824, PubMed:25447992). Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis (PubMed:25447992). May be involved in mitochondrial transport or positioning (PubMed:23568824).

Sequence Similarities

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

Tissue Specificity

Widely expressed in multiple tissues and cell lines.

Cellular localization

Alternative names

MYOHD1, MYO19, Unconventional myosin-XIX, Myosin head domain-containing protein 1

swissprot:Q96H55 entrezGene:80179