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Function

May be involved in processing of pneumocyte surfactant precursors.

Sequence similarities

Belongs to the peptidase A1 family.

Tissue specificity

Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.

Cellular localization

  • Secreted

Alternative names

NAP1, NAPA, NAPSA, Napsin-A, Aspartyl protease 4, Napsin-1, TA01/TA02, ASP4, Asp 4

Target type

Proteins

Primary research area

Oncology

Molecular weight

45387Da