NAT2
Function
Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates (PubMed:12222688, PubMed:7915226). Participates in the detoxification of a plethora of hydrazine and arylamine drugs, and is able to bioactivate several known carcinogens.
Sequence Similarities
Belongs to the arylamine N-acetyltransferase family.
Cellular localization
- Cytoplasm
Alternative names
AAC2, NAT2, Arylamine N-acetyltransferase 2, Arylamide acetylase 2, N-acetyltransferase type 2, N-hydroxyarylamine O-acetyltransferase, Polymorphic arylamine N-acetyltransferase, NAT-2, PNAT