NCAN
Function
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.
Post-translational modifications
O-glycosylated; contains chondroitin sulfate.
Sequence Similarities
Belongs to the aggrecan/versican proteoglycan family.
Tissue Specificity
Detected in cerebrospinal fluid (at protein level) (PubMed:25326458). Brain.
Cellular localization
- Secreted
Alternative names
CSPG3, NEUR, NCAN, Neurocan core protein, Chondroitin sulfate proteoglycan 3