NCOA7
Function
Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.
Sequence Similarities
Belongs to the OXR1 family.
Tissue Specificity
Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.
Cellular localization
- Nucleus
Alternative names
ERAP140, ESNA1, Nbla00052, Nbla10993, NCOA7, Nuclear receptor coactivator 7, 140 kDa estrogen receptor-associated protein, Estrogen nuclear receptor coactivator 1