Ncr1

Function

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Sequence Similarities

Belongs to the natural cytotoxicity receptor (NCR) family.

Tissue Specificity

Selectively expressed by NK cells.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

CD335, Ly94, Ncr1, Natural cytotoxicity triggering receptor 1, Activating receptor 1, Lymphocyte antigen 94, Natural killer cell p46-related protein, mAR-1, NK-p46, NKp46, mNKp46

Database links

swissprot:Q8C567 entrezGene:17086

Other research areas

• Immuno-oncology