NCR2
Function
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Sequence Similarities
Belongs to the natural cytotoxicity receptor (NCR) family.
Tissue Specificity
Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
Alternative names
CD336, LY95, NCR2, Natural cytotoxicity triggering receptor 2, Lymphocyte antigen 95 homolog, NK cell-activating receptor, Natural killer cell p44-related protein, NK-p44, NKp44