Nexn
Function
Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity.
Tissue Specificity
Expressed in brain, testis, spleen and fibroblasts (at protein level). Not detected in liver, kidney or epithelial cells (at protein level).
Cellular localization
- Cytoplasm
- Cytoskeleton
- Cell junction
- Adherens junction
- Cytoplasm
- Myofibril
- Sarcomere
- Z line
- Localizes to the cell-matrix AJ (PubMed:9832551). Not found at the cell-cell AJ (PubMed:9832551).
Alternative names
Nexilin, Nexn