Nfasc
Domain
Homophilic adhesion is primarily mediated by the interaction of the second Ig-like domains.
Function
Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions.
Sequence Similarities
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
Alternative names
Neurofascin, Nfasc