NFIC/CTF

Domain

The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.

Function

Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

Sequence similarities

Belongs to the CTF/NF-I family.

Cellular localization

• Nucleus

Alternative names

• Nuclear factor 1 C-type
• NF1-C
• Nuclear factor 1/C
• CCAAT-box-binding transcription factor
• Nuclear factor I/C
• TGGCA-binding protein
• CTF
• NF-I/C
• NFI-C
• NFIC
• NFI

Database links

• entrezGene:4782
• entrezGene:4781
• omim:600728
• omim:600729
• swissprot:P08651
• swissprot:O00712

Target type

Proteins

Molecular weight

55675Da