NFKBID
Function
Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR). May also regulate TCR-induced negative selection of thymocytes.
Sequence Similarities
Belongs to the NF-kappa-B inhibitor family.
Cellular localization
- Nucleus
Alternative names
IKBNS, NFKBID, NF-kappa-B inhibitor delta, NFKB inhibitor delta, I-kappa-B-delta, IkappaBNS, T-cell activation NFKB-like protein, TA-NFKBH, IkB-delta, IkappaBdelta