NGFI-A-binding protein 1
Domain
The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization.
The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
Function
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.
Sequence Similarities
Belongs to the NAB family.
Tissue Specificity
Isoform Short is found in myeloid leukemia cell line KG-1.
Cellular localization
- Nucleus
Alternative names
NGFI-A-binding protein 1, EGR-1-binding protein 1, Transcriptional regulatory protein p54, NAB1