NIBAN1
Function
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity).
Sequence Similarities
Belongs to the Niban family.
Tissue Specificity
Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney.
Cellular localization
- Cytoplasm
- Membrane
- Lipid-anchor
Alternative names
C1orf24, FAM129A, NIBAN, GIG39, NIBAN1, Protein Niban 1, Cell growth-inhibiting gene 39 protein, Protein FAM129A