NIFK
Post-translational modifications
Sequentially phosphorylated on Thr-238, Thr-234 and Ser-230. Thr-234 is phosphorylated only when Thr-238 is phosphorylated. Likewise, phosphorylation at Ser-230 requires that Thr-234 and Thr-238 are phosphorylated. Phosphorylation enhances MKI67 binding.
Cellular localization
- Nucleus
- Nucleolus
- Chromosome
- Localizes to mitotic chromosomes in conjunction with MKI67.
Alternative names
MKI67IP, NOPP34, NIFK, MKI67 FHA domain-interacting nucleolar phosphoprotein, Nucleolar phosphoprotein Nopp34, Nucleolar protein interacting with the FHA domain of pKI-67, hNIFK