This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin K.
Belongs to the G-protein coupled receptor 1 family.
Tac1r, Substance-P receptor, SPR, NK-1 receptor, Tachykinin receptor 1, NK-1R
Proteins
Neuroscience
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