NKD1
Developmental stage
Expressed in fetal brain, kidney, liver and lung.
Function
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
Sequence Similarities
Belongs to the NKD family.
Tissue Specificity
Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen.
Cellular localization
- Cell membrane
- Cytoplasm
Alternative names
NKD, PP7246, NKD1, Protein naked cuticle homolog 1, Naked-1, hNkd, hNkd1