NLE1
Function
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).
Sequence Similarities
Belongs to the NLE1/RSA4 family.
Cellular localization
- Nucleus
- Nucleolus
Alternative names
HUSSY-07, NLE1, Notchless protein homolog 1