NLRC5
Function
Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
Sequence Similarities
Belongs to the NLRP family.
Tissue Specificity
Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
Cellular localization
- Cytoplasm
Alternative names
NOD27, NOD4, NLRC5, Protein NLRC5, Caterpiller protein 16.1, Nucleotide-binding oligomerization domain protein 27, Nucleotide-binding oligomerization domain protein 4, CLR16.1