NMUR1
Function
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity
Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
GPR66, NMUR1, Neuromedin-U receptor 1, NMU-R1, G-protein coupled receptor 66, G-protein coupled receptor FM-3