NPAS3
Function
May play a broad role in neurogenesis. May control regulatory pathways relevant to schizophrenia and to psychotic illness (By similarity).
Involvement in disease
A chromosomal aberration involving NPAS3 is found in a family with schizophrenia. Translocation t(9;14)(q34;q13).
Tissue Specificity
Ubiquitously expressed in the adult brain.
Cellular localization
- Nucleus
Alternative names
BHLHE12, MOP6, PASD6, NPAS3, Neuronal PAS domain-containing protein 3, Neuronal PAS3, Basic-helix-loop-helix-PAS protein MOP6, Class E basic helix-loop-helix protein 12, Member of PAS protein 6, PAS domain-containing protein 6, bHLHe12