NPY
Function
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Post-translational modifications
The neuropeptide Y form is cleaved at Pro-11 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
Sequence Similarities
Belongs to the NPY family.
Tissue Specificity
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
Cellular localization
- Secreted
- Cytoplasmic vesicle
- Secretory vesicle
- Neuronal dense core vesicle
Alternative names
Pro-neuropeptide Y