NPY1R

Function

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Cellular localization

• Cell membrane
• Multi-pass membrane protein

Alternative names

• Neuropeptide Y receptor type 1
• NPY1-R
• NPYY1
• NPY1R
• NPYR

Database links

• entrezGene:4886
• omim:162641
• swissprot:P25929

Target type

Proteins

Molecular weight

44392Da