Nrxn2
Function
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.
Post-translational modifications
O-glycosylated; contains heparan sulfate. Heparan sulfate attachment is required for synapse development by mediating interactions with neuroligins.
Sequence Similarities
Belongs to the neurexin family.
Tissue Specificity
Brain (neuronal synapse).
Cellular localization
- Presynaptic cell membrane
- Single-pass type I membrane protein
Alternative names
Neurexin-2, Neurexin II-alpha, Neurexin-2-alpha, Nrxn2