Nsf
Function
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack GRIA2 leads to influence GRIA2 membrane cycling (By similarity).
Post-translational modifications
Phosphorylation at Ser-569 interferes with homohexamerization.
Sequence Similarities
Belongs to the AAA ATPase family.
Cellular localization
- Cytoplasm
Alternative names
Skd2, Nsf, Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, Suppressor of K(+) transport growth defect 2, Vesicular-fusion protein NSF, NEM-sensitive fusion protein, Protein SKD2