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NSMAF

Function

Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE.

Tissue Specificity

Ubiquitous.

Alternative names

FAN, NSMAF, Protein FAN, Factor associated with neutral sphingomyelinase activation, Factor associated with N-SMase activation

swissprot:Q92636 entrezGene:8439 omim:603043