NUP210
Function
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
Post-translational modifications
N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides (By similarity).
Phosphorylated at Ser-1881 in mitosis specifically; not phosphorylated in interphase.
Sequence Similarities
Belongs to the NUP210 family.
Tissue Specificity
Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle.
Cellular localization
- Nucleus
- Nuclear pore complex
- Nucleus membrane
- Single-pass type I membrane protein
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
Alternative names
KIAA0906, PSEC0245, NUP210, Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nuclear envelope pore membrane protein POM 210, Nucleoporin Nup210, Pore membrane protein of 210 kDa, POM210