OGN
Function
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
Post-translational modifications
O-glycosylated with a core 1 or possibly core 8 glycan.
Contains keratan sulfate.
Sequence Similarities
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
Tissue Specificity
Bone.
Cellular localization
- Secreted
- Extracellular space
- Extracellular matrix
Alternative names
OIF, SLRR3A, OGN, Mimecan, Osteoglycin, Osteoinductive factor