ompA
Domain
The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
Function
Acts as a fimbriae subunit, allowing adhesion to host cells.
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
Sequence Similarities
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
Cellular localization
- Cell outer membrane
- Multi-pass membrane protein
- Fimbrium
- Antisera against this protein label the whole length of fimbriae.
Alternative names
ompP5, ompA, Outer membrane protein P5, OMP P5, Fimbrin, Outer membrane porin A, Outer membrane protein A