ompA
Domain
The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
Function
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
Required for conjugation with F-type plasmids; probably serves as the mating receptor on recipient cells.
Sequence Similarities
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
Cellular localization
- Cell outer membrane
- Multi-pass membrane protein
Alternative names
STY1091, t1850, ompA, Outer membrane protein A, Outer membrane porin A