OPCML
Function
Binds opioids in the presence of acidic lipids; probably involved in cell contact.
Involvement in disease
Ovarian cancer
OC
The term ovarian cancer defines malignancies originating from ovarian tissue. Although many histologic types of ovarian tumors have been described, epithelial ovarian carcinoma is the most common form. Ovarian cancers are often asymptomatic and the recognized signs and symptoms, even of late-stage disease, are vague. Consequently, most patients are diagnosed with advanced disease.
None
Disease susceptibility is associated with variants affecting the gene represented in this entry.
Sequence Similarities
Belongs to the immunoglobulin superfamily. IgLON family.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
IGLON1, OBCAM, OPCML, Opioid-binding protein/cell adhesion molecule, Opioid-binding cell adhesion molecule, IgLON family member 1