OPG147
Function
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).
Post-translational modifications
Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes.
Sequence Similarities
Belongs to the orthopoxvirus OPG147 family.
Cellular localization
- Virion membrane
- Single-pass type III membrane protein
- Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis.
Alternative names
VACWR140, A21L, OPG147, Virion membrane protein OPG147