Opn1sw
Function
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (PubMed:21219924, PubMed:25416279). Involved in ensuring correct abundance and localization of retinal membrane proteins (PubMed:25416279). May increase spectral sensitivity in dim light (PubMed:11055434).
Post-translational modifications
Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Tissue Specificity
Expressed in the inner and outer segments of cone photoreceptor cells in the retina (at protein level).
Cellular localization
- Cell membrane
- Multi-pass membrane protein
- Photoreceptor inner segment
- Cell projection
- Cilium
- Photoreceptor outer segment
- Cytoplasm
- Perinuclear region
Alternative names
Bcp, Opn1sw, Short-wave-sensitive opsin 1, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, Short wavelength-sensitive cone opsin, BOP