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Function

Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (PubMed:21219924, PubMed:25416279). Involved in ensuring correct abundance and localization of retinal membrane proteins (PubMed:25416279). May increase spectral sensitivity in dim light (PubMed:11055434).

Post-translational modifications

Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Tissue specificity

Expressed in the inner and outer segments of cone photoreceptor cells in the retina (at protein level).

Cellular localization

  • Cell membrane
  • Multi-pass membrane protein
  • Photoreceptor inner segment
  • Cell projection
  • Cilium
  • Photoreceptor outer segment
  • Cytoplasm
  • Perinuclear region

Alternative names

Bcp, Opn1sw, Short-wave-sensitive opsin 1, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, Short wavelength-sensitive cone opsin, BOP

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

38922Da

We found 1 product in 1 category

Primary Antibodies

Application

Reactive species

Search our catalogue for 'Opn1sw' (1)

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