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Opn1sw

Function

Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (PubMed:21219924, PubMed:25416279). Involved in ensuring correct abundance and localization of retinal membrane proteins (PubMed:25416279). May increase spectral sensitivity in dim light (PubMed:11055434).

Post-translational modifications

Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Tissue specificity

Expressed in the inner and outer segments of cone photoreceptor cells in the retina (at protein level).

Cellular localization

  • Cell membrane
  • Multi-pass membrane protein
  • Photoreceptor inner segment
  • Cell projection
  • Cilium
  • Photoreceptor outer segment
  • Cytoplasm
  • Perinuclear region

Alternative names

  • Short-wave-sensitive opsin 1
  • S opsin
  • Blue cone photoreceptor pigment
  • Blue-sensitive opsin
  • Short wavelength-sensitive cone opsin
  • BOP
  • Opn1sw
  • Bcp

Target type

Proteins

Molecular weight

38922Da