OPN4

Function

Photoreceptor that binds cis-retinaldehydes (PubMed:15674244). Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light (By similarity). May be involved in the optokinetic visual tracking response (By similarity). May be involved in the regulation of retinal hyaloid vessel growth and regression (By similarity).

Sequence Similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Tissue Specificity

Expressed in the retina.

Cellular localization

• Cell membrane
• Multi-pass membrane protein
• Cell projection
• Axon
• Cell projection
• Dendrite
• Perikaryon

Alternative names

MOP, OPN4, Melanopsin, Opsin-4

Database links

swissprot:Q9UHM6 swissprot:Q14D01 omim:606665 entrezGene:94233