Osteoclast-stimulating factor 1
Domain
The SH3 domain mediates interaction with SMN1.
Function
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
Tissue Specificity
Ubiquitously expressed. Present in osteoclasts (at protein level).
Cellular localization
- Cytoplasm
Alternative names
Osteoclast-stimulating factor 1, OSTF1