OTX1

Developmental stage

Embryo.

Function

Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Sequence Similarities

Belongs to the paired homeobox family. Bicoid subfamily.

Tissue Specificity

Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level).

Cellular localization

• Nucleus

Alternative names

Homeobox protein OTX1, Orthodenticle homolog 1, OTX1

Database links

swissprot:P32242 entrezGene:5013 omim:600036 swissprot:P32243 swissprot:Q53TG6 entrezGene:5015