Pantetheinase
Function
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
Post-translational modifications
N-glycosylated.
Sequence Similarities
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
Tissue Specificity
Detected in kidney (at protein level). Ubiquitous.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
Pantetheinase, Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, Vnn1